Catching fear memories
نویسندگان
چکیده
منابع مشابه
Are fear memories erasable?–reconsolidation of learned fear with fear-relevant and fear-irrelevant stimuli
Recent advances in the field of fear learning have demonstrated that a single reminder exposure prior to extinction training can prevent the return of extinguished fear by disrupting the process of reconsolidation. These findings have however proven hard to replicate in humans. Given the significant implications of preventing the return of fear, the purpose of the present study was to further s...
متن کاملChasing "fear memories" to the cerebellum.
T cerebellum has long been known as a center of fine motor control and sensory-motor integration. It also is appreciated as essential for the acquisition and expression of conditioned eye-blink responses, a type of discrete sensorymotor learning (1, 2). Recently, the cerebellum also has been implicated in acquiring (3–5) and expressing (6) ‘‘emotional’’ associative learning, which is commonly b...
متن کاملErasing fear memories with extinction training.
Decades of behavioral studies have confirmed that extinction does not erase classically conditioned fear memories. For this reason, research efforts have focused on the mechanisms underlying the development of extinction-induced inhibition within fear circuits. However, recent studies in rodents have uncovered mechanisms that stabilize and destabilize fear memories, opening the possibility that...
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Fear inhibition is markedly impaired in adolescent rodents and humans. The present experiments investigated whether this impairment is critically determined by the animal's age at the time of fear learning or their age at fear extinction. Male rats (n = 170) were tested for extinction retention after conditioning and extinction at different ages. We examined neural correlates of impaired extinc...
متن کاملThe ontogeny of fear-potentiated startle: effects of earlier-acquired fear memories.
Research has shown that learned fear emerges in a response-specific sequence. For example, freezing is observed at a younger age than is potentiated startle (P. Hunt & B. A. Campbell, 1997). The present study shows that the age at which a specific learned fear response emerges is influenced by the animal's early experiences. Specifically, fear potentiation of startle emerges earlier in developm...
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ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2017
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn.2017.95